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John Griffith (1810-1872) was one of the first settlers of Monroe County, arriving in 1819. His father, also named John, built one of the first combined grist and saw mills in the county. He died in 1865.
In 1833 John Griffith married the former Hetty Wampler and five years later they moved to a 320-acre farm, on land north of Bloomington, where he remained until his death. He is buried in Griffith Cemetery which overlooks SR 37.
His wife, known as "Aunt Hetty", survived him by 32 years, and had a reputation as a folk doctor, with expertise in mixing medicines from herbs, barks, and roots.
They had twelve children: Deborah L. (Gray), Esther (Cox), Melinda C. (Cox), Tillman H., Mary E. (Gray), Theresa A. (Cox), Lucinda J., Louis C., Lucretia E., Margaret A., and two dying in infancy.
Griffy Creek is probably a corruption of Griffith's Creek, named after this family.